Handanovic has been linked with Barcelona, while teammate Fredy Guarin is interesting Tottenham.
Moratti said: "They are fundamental players, especially Handanovic. Guarin also gives the impression he can be among the best around if he finds some consistency. He's one of the most promising players we have.
"Bad luck was a factor in the injury crisis, but any setback is down to a number of factors. I am trying to understand what was behind all this."