United saw off the Latics comfortably earlier this season with a 4-0 win at Old Trafford, but the squad's memories of the last visit to the DW Stadium are less memorable.
"Last season when we went there we didn't play well and Wigan were in good form and we lost 1-0," recalled Ryan Giggs on MUTV. "We knew they were in a false position going into that game and that they were playing well. When you don't turn up and you play a team in good form you're always going to come unstuck no matter who you play in the Premier League. It was tough especially when you consider our [good] record there and it undoubtedly contributed to us losing the title.
"Wigan are a tough team to play against. They play with a different system to what we're used to and they play it well. I'm surprised that they're down there [towards the bottom of the table] considering the tough game they gave us last season and this season at Old Trafford where they played well. Roberto Martinez has got his own system and it's very tough to play against, so we'll need to play well."