Sir Alex Fergusonâ€™s side will seal a place in the last 16 if they beat Celtic tomorrow.
And Giggs, who won his second winnerâ€™s medal in Moscow last May, insists United have the ability and star quality to make history.
Giggs, 34, said: â€śNo team has retained the Champions League but thatâ€™s our challenge.
â€śWe need to use the experience we had last year, keep the desire and hunger that we had, and use it.
â€śItâ€™s not going to be easy but we feel we have a great chance.â€ť