Clarke took the brave step of dropping Peter Odemwingie to the bench despite his two goals to sink Southampton last Monday, and was rewarded as James Morrison and a Gary Caldwell own goal steered his side to victory.
Clarke said: "We've got a lot of options in our squad which gives me some fantastic problems.
"We play with intensity going forward and I was a little concerned the ones who played on Monday night might be carrying fatigue. I've got a quality squad and I have to use them. They know they're all valuable in terms of the club going forward."