Barca are back on top of the table following the 3-1 win.
"I don't know how the defeat will affect Real Madrid. I can only talk about my own sensations with our team, which are very good. For us it was really important to win," said Iniesta.
The midfielder is eager to win the Club World Cup this week after missing out on 2009's triumph due to injury.
"Personally, it's an extra motivation. That year I had lots of problems with injuries, and I really hope I can play in the Final."