With such high-profile matches coming thick and fast, German centre-back Mertesacker accepts focus will be the key to sustaining a good run of form in all competitions.
"There is no special way to do more or less, when you behave like a professional you have to continue what do you do through the whole season so you are ready for these big clashes," he said in the Arsenal matchday programme.
"It is it is just up to you to continue what you have done - the concentration, the tension and the atmosphere will be bigger than normal, but I am still relaxed because we have had heavy schedules through the season and we have been able to pick one game at a time and think 'the next game is the really important one'.
"If there are four big games coming up, you have to isolate each game and take one at a time.
"You have to switch on quickly and try to switch off for maybe 24 hours and then (get) switched on again, that is really important during heavy schedule.
"I think our group of players has the potential to do it and we have shown that through the season we have the ability to make these games special for us."
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