However, manager Mauricio Pochettino says he will have both his star attackers available when they take on Brugge in Belgium.
City's group also contains Manchester City and RB Leipzig.
"They came back to Paris on Friday night and trained today. I'm happy because even if they're tired, they don't have any physical problem," said Pochettino, per the Evening Standard.
"They will be here for Wednesday's game."
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