Bielsa has dubbed Sunday's clash as a "Classico".
He said, "For every game, we go into it trying to score and trying to avoid conceding. Of course what happened in that last game, we have it present in our minds. You have to implement your ideas and try to impose them.
“You have to recognise the characteristics of the opponents forwards and try to organise our players on the field, so they can pick up the protagonists in Manchester United's play.
“We've tried to match them up with players from our team who are up to the challenge of neutralising them.
“I know perfectly what it means to play in a classic game. There is something that has to build up through many years to lay in the feeling of the fans, and the effect that the result will have on the emotions of the people."