Inter need to win to secure Champions League qualification, Empoli the same to stay up.
Spalletti said: “They are in good shape and clearly the sheer importance of what is at stake wipes out everything that came before.
“All of that is irrelevant now, all that matters is how you prove yourself in these 90 minutes. We tried to fill our heads with what we need to reach the Champions League.
“We have to believe in ourselves and have the mental strength to get the result. It's important, because results stay with you, they are tattooed on your skin for the rest of your career. Both the Coach and players will carry that result on our CVs for the rest of our lives."