Granada coach Tony Adams is demanding the players fight to the end.
They face Sevilla tonight, heir first of six fixtures to close the seven point gap separating themselves from safety.
"We are going to continue fighting, I will support my players as long as they give me one hundred percent themselves," Adams told his pre-match press conference.
"[Granada have to be] very strong in attack and defence, [against] a very good and dangerous team that play very well.
"There is nothing to lose."
Even if they are relegated, the 19th-placed team assert that they are prepared for next season with work already underway to build a fresh squad.
"Forty percent of the squad is complete for next season, regardless of the division, and the majority are Spanish," Adams noted.