The Liverpool legend has put pen to paper on a two year contract that will see him take charge of the A-League side. Fowler will take up his position in a month, when the current season comes to an end.
The 44-year-old spoke about his delight at securing the role.
Fowler said in a statement: "I'm really looking forward to the challenge and am determined to bring success to a club that has such a proud history in the Hyundai A-League.
"I'm really keen to get started and make a difference. My family and I have already experienced living in Queensland, so I'm really happy to be returning and being part of the Brisbane Roar family."
Brisbane chief executive David Pourre added: "I'd like to take this opportunity to congratulate and welcome Robbie to our proud and successful football club.
"BRFC is confident that we have appointed an outstanding person and someone who is hungry to succeed. I know our members, supporters, sponsors and fans will be excited for season 2019/20."