Busquets believes Barcelona can compete on every front come the end of the season.
The Catalan club were 1-0 winners over Granada in Quique Setien's first match in charge on Sunday night.
"The board wanted this and, whoever [came in as coach], we hope the impact is positive," Busquets said.
"We're able to win every trophy [this season]."
Ernesto Valverde was often criticised for his style of play while Setien has introduced a more possession-based system.
"There's nothing to compare. Each coach has their own style of their own way of seeing football," Busquets said.
"You've seen what the boss asked us to do. If we're talking about it, it seems like we've taken the game [to the opposition].
"I'm delighted with what Ernesto did and now I'm the same with Setien."