The Molineux outfit defeated United twice last season, but Jota says they are a much different outfit after a productive summer.
"I don't think we have that line of thinking (about last season)," he said. "This is a new season, so nothing to do with the last one.
"They are very strong at the moment, with their first result of the season, so I think it's going to be hard for us.
"It's a new season so (United have) had more time to work with the players. (Ole Gunnar Solskjaer) made his own changes, every team in the transfer market tried to improve their team, so we know it's going to be hard and we have to understand we're going to face a big team and it's going to be hard."