The two clubs will meet in the FA Cup fifth-round at Molineux and then in the Premier League at St. Mary's on Saturday.
Ward-Prowse has scored four free-kicks this season, and Nuno is wary of the threat.
"How do you stop it? A good wall, and then prevent the ball going inside your goal - and pray!", Nuno told reporters in a press conference when asked about Wolves' upcoming adversary.
"He is a specialist. He is a very good kicker of the ball. He has shown his quality. It can happen, a foul is a foul, and you have to just prepare yourself, organise your wall properly and then do your job."