Former England midfielder Wilkins thinks previous experience of working under Jose Mourinho will give Villas-Boas a base to build from in his own tenure as manager.
"His training drills will be organised, he has worked with Mourinho and the players were well into the Mourinho philosophy and he will know what the players require," he said.
"The bigger challenge will be when the games start and whether he can respond to the tactical situations he finds himself in.
"He knows what it's about from within the club and he will run the footballing side. It's a wonderful league because no two games are the same and I'm sure he'll enjoy that."