The defender is a loan target for West Ham ahead of the January transfer window, says the Manchester Evening News.
Wan-Bissaka, 24, has only played four minutes this season and last started for United in the 1-0 defeat at Everton on April 9. His first start under Erik ten Hag was in the friendly defeat to Cadiz on December 7.
United informed Wan-Bissaka he was free to leave before the end of last season and there was reputed interest from West Ham in the summer.
West Ham have a close relationship with Wan-Bissaka's representatives Unique Sports Management, which oversaw Maxwel Cornet's transfer from Burnley in the summer. Michail Antonio and Aaron Cresswell are also both represented by the same agency.