Lucas Moura came off the bench in the second half to haul Spurs level and Guardiola reacted by hooking Aguero for the Brazilian.
The 31-year-old was visibly annoyed as he left the pitch and attempted to barge past his manager on his way into the stands.
Guardiola was shrugged off in his attempts to grab Aguero by the arm and has to resort to putting his hand on his strikers chest.
The Argentine retaliating by giving the Spaniard an earful and assistant manager Mikel Arteta is forced to step in and separate the two.
Everyone is being silent on what happened between Pep & Kün Aguero But when pogba and Mourinho had issues the whole pl was upside down #MCITOT#guardiola#premierleauge#ManchesterCitypic.twitter.com/wMzdGloZrS— Jeffrey (@baaadcaptain) August 17, 2019