Arsenal will play their Europa League group game against Vitoria SC at a time on Wednesday, to avoid traffic congestion in Portugal.
The tie will be played at 15:50 GMT on 6 November - a day earlier than the other 23 fixtures taking place.
Portuguese rivals Braga host Besiktas at the Municipal Stadium on Thursday, 15 miles from Vitoria's home ground.
As well as moving the fixture a day earlier, the game is kicking off at an unusual time to avoid broadcasting clashes with the Champions League.
Europa League matches usually take place at either 17:55 GMT or 20:00 GMT on Thursdays.