Spurs head to the Emirates on the back of a shock 1-0 loss at home to Newcastle.
Sissoko said: "Look, when you lose one game, especially at home, you have to react straight away. That's what good teams do and hopefully we can do it next week.
"It's going to be a tough game, a massive game, everyone is waiting for it - the fans, the Club, the players.
"Derbies are always exciting. We'll be ready, hopefully we'll win and take three points before the international break."