PSG and United meet next month in the Champions League round of 16.
Lloris told RMC: "Manchester is still a very big institution, one of the biggest clubs in the world.
"They are always present in major events. Afterwards, inevitably in a season, there are ups and downs. They have known strengths and they will come back even stronger. They have shown it for a few games but Paris is a very very good team with very great players. It will be a very nice open tie."