Spurs go to City defending a 1-0 lead from the first-leg of their Champions League quarterfinal.
"It is the type of game all players want to play in," Lloris said.
"It is going to be about details – the same as the first leg. We need experience, nerve and spirit.
"The spirit has been fantastic the last few weeks but you can never feel comfortable. You always need to push your limits. That is going to be the case against City."