Tottenham take a 1-0 lead to the Etihad stadium.
Alli and Harry Winks missed the Huddersfield win with hand and groin injuries respectively and Pochettino said: "We'll see with Dele.
"I'm not sure. He is doing some training sessions (with a protective cast) and needs to be comfortable. It's a bit painful. He broke a bone in two places.
"Harry (Winks) is not a big issue but not easy."