Kane, who has been playing through niggling injuries, will be involved for Tottenham at Dinamo Zagreb in the Europa League on Thursday and at Aston Villa on Sunday before reporting for international duty on Monday.
"I have no control," said Mourinho. "If I could choose, I would love them all to go because I love my players to be involved in the national teams. It's a question of pride for them and a plus for the club.
"Of course if we could choose we wouldn't like the players to play three matches, but it's in the hands of the international managers.
"I cannot do Gareth's work. He doesn't make comments about my selection or give opinion about should I play or rest this England player or the other.
"He never makes any comment so I don't feel very comfortable doing that in this moment. He does what he wants, what he thinks is best for the team. I believe he has a good relationship with Harry, good communication.
"I hope that between them and without me in the middle they can find some compromise to protect the players a little bit."
Tottenham won 2-0 in Europe and Mourinho has confirmed his top scorer will be involved in the second leg.
"He plays tomorrow," said the Spurs boss. "It is open and it is a very important game. I don't feel it's game over. We don't go there to defend a lead, we go there to win a game. If we qualify with a defeat in this game, I will not be happy."
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