Swansea striker Jordan Ayew was on target for Ghana as they secured a 2-0 win over Guinea-Bissau.
The Black Stars emerged in the top spot of Group F, edging out Cameroon for the position.
Ghana had been enduring a difficult African Cup of Nations before this game, drawing their first two matches.
However, they overcame early nerves to seal the points in this clash.
Goals from Thomas Partey and Ayew were enough to get the win, despite Guinea-Bissau hitting the post three times!