Tottenham will face Hearts in an all British Europa League qualifier.
Hearts manager Paulo Sergio, who declared his passion for British football when he took on his role on Tuesday, was delighted.
"This is a very interesting draw for us, for sure," Sergio told Hearts News.
"No matter who we were drawn against it was going to be a very difficult tie but it is a match which I am sure will capture the imagination.
"There is not much travelling involved for the supporters and of course there will be the Scotland-England rivalry as well."
Fulham's reward for getting past RNK Split with a comfortable 2-0 home win is a clash against Ukrainian outfit Dnipro Dnipropetrovsk.
Martin Jol's side, who have been in action in the competition since qualifying started at the end of June, will play the first leg at the Dnipro Arena, before returning to Craven Cottage.
Stoke City are facing a trip to Switzerland after being paired with FC Thun, with the first leg at Arena Thun.
Tony Pulis' men, making their first appearance in Europe after reaching the FA Cup final last season, while Thun finished fifth and are coached by the veteran Swiss Bernard Challandes.
Carling Cup winners Birmingham City, who will compete despite their relegation to the Championship, will juggle their second-tier slog with a clash against Portuguese club Nacional.
