Ramos is the captain of the Spanish national team and he remained an integral part of the former Barcelona coach's plans during his first tenure in charge.
"My relationship with Ramos is very good, as with 99.9 per cent of the players," Luis Enrique said in a Q&A.
"Sergio is the captain. I only knew him from references and from having played against him.
"When I met him, I was pleasantly surprised; there is a reason why he holds [Spain's] record for international appearances.
"I was surprised by his leadership skills and personal qualities."