While Souness recognises the threat Mikel Arteta's side will pose on Saturday, he believes the Reds' frustration from their last defeat to West Ham will blow the Gunners away.
Souness told Sky Sports' Essential Football Podcast: "I think Liverpool will be the angry team having lost last time out where they were not at their normal standards.
"But given the teams they (Arsenal) have been playing of late, they're not exactly top of the table teams: an average Leicester this year, a draw with Brighton, beating Watford, Norwich and beating a very poor Spurs team.
"They've got some confidence from winning games and they're sitting in a very healthy position in the league but the hard part of their season is ahead.
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