Souness believes sooner or later that Solskjaer is going to run out of patience with his error-prone No 1.
He said: "I'm a fan of Dean Henderson.
"It's only a matter of time. You look at Sheffield United's plight, he is the single biggest reason why they are where they are.
"David de Gea is making mistakes, a manager can only tolerate that for so long. If the goalkeeper is making mistakes, it impacts the rest of the team."