"We've had lots of games at Wembley against them and, of course, we've had quite a few cup games against them in the last couple of seasons as well," Ole told MUTV, ahead of Tuesday's Premier League clash at Brighton & Hove Albion.
"They're a team that will know a lot about us and they're a team we know a lot about too. We're looking forward to being at Wembley, any team who you draw there would be a top team anyway. I can't wait, it's been a while."
Asked if he was confident ahead of the fourth clash with the 2018 winners, Solskjaer replied: "Yes. Of course we are.
"One, we've played quite a few good games against them lately and we know that we're competitive and have done really well against them and two, we have some really good momentum, we are building that and we're in good form.
"The players are getting fitter and fitter and improving. The games are coming thick and fast and of course when you go to Wembley you know that a place in the final is at stake so we're going to go for it."