Manchester United boss Ole Gunnar Solskjaer has named Edinson Cavani and Dean Henderson in his starting XI for today's clash with Tottenham.
Cavani starts in attack, with Mason Greenwood moving to the bench, and Marcus Rashford is fit enough to make the team. Paul Pogba is likely to operate on the left-hand side as Fred and Scott McTominay form the two defensive midfield slots.
Henderson gets the nod in goal, after David De Gea featured in the Europa League win over Granada on Thursday night.
There is no Daniel James in the matchday squad but Juan Mata, who has not played since the win over Newcastle United in February, is among the substitutes again.
Solskjaer said, "Freshen it up, carry on doing things we have done.
"Dan had an injury on Thursday night so he couldn't be with us, Mason [Greenwood] also had some niggles so we gave him some rest from the start.
"I think everyone is fine, we didn't do a lot on the training pitch, we had the meetings but rest and the recovery is the name of the game. We will be ready.
"It will be the game that we make it. We wan to go out and dominate possession, create chances, but we have to defend well. We know their front players they are dangerous It will be hard to stop, but we have to do that properly."
Tottenham: Lloris (c); Aurier, Rodon, Dier, Reguilon; Hojbjerg, Ndombele; Lo Celso, Lucas, Son; Kane.
Substitutes: Hart, Alderweireld, Tangana, Winks, Sissoko, Dele, Lamela, Bale, Vinicius.
United: Henderson; Wan-Bissaka, Lindelof, Maguire (c), Shaw; Fred, McTominay; Rashford, Fernandes, Pogba; Cavani.
Substitutes: De Gea, Telles, Tuanzebe, Williams, Amad, Mata, Matic, van de Beek, Greenwood.