A minute's silence will take place before kick-off in their memory, while both teams will wear black armbands.
"It's a big day for everyone and always an emotional one," said Solskjaer.
"It's only the fourth time the game is played on the actual anniversary and it's important we put on a fitting performance and hopefully we can honour them with the result."
"It's such an important part of our history of the club and we have spoken to the players who come into the club, who've not been here and are part of this anniversary," added Solskjaer.
"Hopefully we can put the team out that shows the Manchester United spirit. We have six or seven academy graduates and hopefully they will lead us on."