The Red Devils have been accused of inadequacy, both in work-rate and attitude, after Sunday's 4-0 loss to Everton, which dented their chances of finishing in the top-four.
Speaking ahead of Wednesday's clash with Manchester City, Solskjaer denied his squad have not maintained the club's standards.
"Now is not the time to talk about, or make, wholesale changes in the squad because [that squad] has been doing so great.
"City and Liverpool have taken more points than us in the last 18 games or whatever it is, and that's it. That's a great effort by the boys.
"Where we were when we came in, we've really given it a go, and I've got say that you can see loads of Man United standards – the DNA – in many of these players.
"But… as I've said: of course you have to get players in and some players will have to go out."