As many as six players could leave Manchester United at the end of the season with uncertainty over the futures of the likes of Ander Herrera, Juan Mata and Alexis Sanchez.
Boss Ole Gunnar Solskjaer said discussions with players coming out of contract would not be a distraction for his side, adding: "Contract talks will just go on. We are looking forward, knowing we can create a special atmosphere here.
"Playing at Old Trafford in a knockout stage, floodlights, hopefully a bit of rain, will make for a special evening."