Maguire suffered a knock in Saturday's win over Newcastle United, while Cavani is still working himself back to full fitness after taking part in his first training session on Sunday.
"We're a little bit depleted but we've got more than enough players," said Solskjaer to reporters.
"We hope that the players won't be away for too long. Edinson needs a few more days training before maybe we can think about the weekend, hopefully Harry can and Mason as well but we're not sure about that."
United famously overturned a 3-1 aggregate deficit the last time they played in Paris in 2019.
The Norwegian added: "That's history for us, it's in the past, so great history, great game but it has no impact whatsoever on this game.
"We know we're a different team, they are a different team, it's a different stage of the competition, it's of course also without fans so it's going to be a different game."