Manchester United manager Ole Gunnar Solskjaer says it will be impossible for him not to rotate his players this week.
Following Sunday's win over Aston Villa, the Red Devils will face Leicester City on Tuesday, Liverpool on Thursday and Fulham next Tuesday.
"I think everyone is capable of doing a Thursday-Sunday," Solskjaer said. "But to put in Tuesday is more or less demanding too much of them. Adding Thursday is impossible - absolutely physically impossible.
"So I have to now make sure that I don't run the risk of getting injuries. So recovery time, more or less all the time you have, two days in between and play on the third day. At this level, it is impossible. The boys who played Thursday night and today will not play 90 minutes on Tuesday, for sure.
"There's no training. It's [in the] classroom. Now you're a teacher. It's the sports scientists - they do their job, they have all the facilities and have the help that the players can get. We will sit down on Tuesday afternoon and see who is ready. I can have a picture in my mind now theoretically, but it might be that things could crop up tomorrow after this game that we don't know until tomorrow."