And Solskjaer acknowledges that a win over the Spanish side, who beat them in the Europa League final last season, could be vital to United reaching the knockout stages.
Asked if the Young Boys result increased the pressure on United to get a positive result tomorrow, Solskjaer said: "Yeah, you're right. It's a group stage, there's only six games, you need 10, maybe 12 points to go through most likely and we lost three points last time.
"Atalanta and Villarreal drew last time too, Villarreal [getting] one point at home maybe isn't enough for them to say a draw [on Wednesday] is good enough for them either. It's two teams that will be going for three points.
"If you end up with zero or one point from the first two games, you need to win the last four, probably. It's still not a must-win game but it's a very important game definitely. As I said after Young Boys, home games, if you get three wins at home and you win one away game, you should be through.
"The focus is on three points, we've been looking at Villarreal again of course, looking at the final, looking at what we can do better, what was good in that game and we'll get a good response from the weekend of course."
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