Ozil was helped off the pitch early in the second half of a 1-1 draw with Antalyaspor.
The 32-year-old went down awkwardly on his ankle following a challenge from opposition forward Fredy.
The incident compounded what has been a frustrating start to Ozil's Fenerbahce career.
Ozil has yet to register a goal or assist in his seven appearance since signing a three-year contact with the Turkish giants.
But the German should be given sympathy as he had not played for nine months prior to arriving in Istanbul.
Mesut Ozil just stretchered off injured.
Not a great day for him, he'd earlier missed a big goal scoring opportunity. pic.twitter.com/9D4VcF38GC
— Gilles (@GrimandiTweetss) March 4, 2021
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