Atletico Madrid manager Diego Simeone has admitted that captain Koke is likely to miss their Champions League Round of 16 first leg against Manchester United in Madrid.

The Spanish champions are set to take on interim coach Ralf Rangnick's Red Devils, as they hope to progress into the quarter finals.

However, an injury and COVID-19-ravaged Atleti side will also be without Koke, who picked up a thigh injury in their 3-0 win over Osasuna at the weekend.

"Well, [Thomas] Lemar is coming back from COVID. [Yannick] Carrasco is suspended, Koke unfortunately is not going to be with us because he's got an injury," Simeone told reporters.

"We have many other players who are looking forward to playing, for this opportunity to show their ability. I'm excited about that."