Lopetegui was speaking after last night's 4-0 defeat.
"They won deservedly. We started badly and only started the match when we were down 0-2. They scored twice more and punished us harshly. It is a team designed to win the Champions League, and when they saw a place to run, they hurt us," said Lopetegui.
Sevilla's working conditions were also challenged further shortly before the start of the match, as goalkeeper Tomas Vaclik had to retire with an injury.
Therefore, 20-year-old Alfonso Vacas had to step up.
"We have had many challenges and it is a reality that we have to fight with. It is a nuisance that we have had and are suffering from before. Vaclik told us that shortly before the start of the match and Alfonso had nothing to do with the defeat. He had a good match."