Real go to City needing to overturn a 2-1 deficit to reach the Champions League quarterfinals.
"I think when Zidane came [back], he got that chemistry back in place and after corona, I think Madrid came out solid, when Barcelona came out a bit segregated," he told Stats Perform News.
"Obviously, when the club with players like [Sergio] Ramos and [Karim] Benzema smell the opportunity against that rival then that creates a motivation that they used and brought it home.
"Ramos and Benzema have been key, key players but, as I said, the whole team has shown a pretty solid shape.
"If you look at them without the results they have now, they are considered definitely [among] the favourites, Manchester City as well - these are two top teams in the world.
"It's going to be tough to go there and turn it around, but nothing is impossible in that sense. But also, Manchester City need to make up for the average season, if you can call it that.
"They can do it, but it's tough."