That's according to Okdiario's chief pundit Eduardo Inda, who speaking on El Chiringuito, revealed Isco's plans for next month.
"Isco has commented to a very trustworthy locker room teammate that he wants to leave in January, and if an offer comes from Pep Guardiola and City in January he leaves," said Inda.
"Real Madrid, if there is an offer, would be willing to study the possibility of selling him.
"I think that with Isco we are talking about €150-180m because of the age and quality he has. In the locker room right now he does not have the best relationship, especially with the hard core.
"Isco thinks: 'If they make me stay, nothing happens either', because like (coach Santiago) Solari they are going to throw him out in June."