Real Madrid will seek buyers this summer for Isco.
Estadio Deportivo says Real Madrid are prepared to let Isco go for a fee of around €20m in the summer.
Madrid were prepared to let the player go for a fee of around €20m in January and will demand the same price in the summer.
The report also claims that Isco is likely to have to take a wage-cut to leave Real in the summer.
Everton have long been linked with a move for the Spain international, who has only played 13 minutes in the Champions League this season.