The right-back came off after 25 minutes before in what was just his fifth match since his return, being replaced by Lucas Vazquez.
He started this season injured and was unavailable for Los Blancos' first match of the season against Alaves, but returned at Levante on August 22.
It appeared that his substitution may have just been a precautionary measure, although it remains to be seen whether that is the case or whether he has in fact suffered another muscular injury.
Need a VPN? Or seeking to switch? Then support Tribal Football by clicking here to sign up with our official partners NordVPN. Not only will you receive the best VPN experience, but also great discounts by signing up via Tribal Football. Thanks for your support!