Lionel Messi and Cristiano Ronaldo won the award for 10 years in a row between 2008 and 2017, claiming five apiece in that time, but the pair saw their duopoly broken last year as Madrid midfielder Luka Modric took home the prestigious trophy in a ceremony in Paris last September.
"If Van Dijk wins it, it will be on sufficient merit," Ramos said at the launch of his new Amazon Prime documentary, in quotes published by Marca. "Great defender.
"As a defender, it's harder.
"It seems as though it's not just Messi and Cristiano [now]. It seems there's a route opening [for others]."
However, he added: "It makes you think [when you realise] that no Spanish players have won it.
"It's an individual prize and it's not really known what is being recognised."