The Gunners travel to the Serbian capital for the first time since the 1978/79 season to face Red Star Belgrade. The supporters of the one-time European Cup champions are renowned for the noise they make at the Rajko Mitić Stadium, but Wenger says it will not be a factor for his players.
"The support of the team always has a positive impact, but we have the habit to deal with that – we have these stadiums in England and we have long experience in the Champions League," said the Frenchman.
"I don't think that will have a negative impact on us. But of course, we are in a country which has a big football tradition, has produced fantastic players in history, a country that knows team sport and knows football very well.
"So we expect of course a game with huge commitment from everybody."