Queens Park Rangers chief executive Lee Hoos believes the current coronavirus crisis is a "seminal moment" for the game.
Many clubs are struggling financially as they cannot hold games, with ticket sales being a significant source of income.
The non-league season is already cancelled, while the Premier League and below divisions are still figuring out ways to resume and complete seasons.
"Financial crisis or recession, football has been immune in the past," Hoos told the Evening Standard.
"Owners just put in more money. Now they can't. That's it, we've reached the seminal moment.
"Football probably has a major reboot [coming]. It has to. It can't go on. The big lesson of [this crisis] is, 'We're not immune'. This is the big reckoning. You have to stand on your own two feet."
"It's just a cash squeeze everywhere," Hoos went on to say.
"Not only are you losing the football income, but the business income which feeds the beast."