The Championship side hammered their relegation rivals in a one-sided display at the DW stadium on Tuesday, which saw them seven-up at the break.
While Wigan are now camped firmly in mid-table in 13th, they face an impending 12-point penalty for going into administration.
Former Hull player David Meyler questioned what his old side were doing, blasting them "unacceptable" on Twitter for "throwing in the towel".
Pilkington, a former Manchester United junior, responded: "Agreed mate not good enough but when a group of 30+ men come together to fight for each other because they feel like they've been f***** over it builds a bond strong enough to do what it takes."
The result left Latics, with two games remaining, on 57 points, 12 points clear of 22nd place - occupied by Hull, who lay a point adrift of safety.