Villa are already into the Carling Cup final and are chasing a top four finish this season.
But O'Neill said: "We're going to try to win the game. There might be a couple of enforced changes and I might make another couple as well.
"But overall we still want to compete in the competition. We have reached a Wembley final in one competition and we want to try and do what we can to do as well as possible in another."