Napoli assistant manager Gigi Riccio admits they were poor for defeat to Lazio.
Lazio were comfortable 2-0 winners on Sunday via goals from Ciro Immobile and Luis Alberto.
“Rino is battling this eye problem, it'll take a few more days and hopefully it'll all return to normal soon," said Riccio.
“Lozano had a heavy knock to his ankle and he's going for tests."
Mexico international Lozano was spotted leaving the Stadio Olimpico on crutches.
“It wasn't the usual Napoli tonight, we were too slow, predictable, easy to read, lost the ball repeatedly, especially in positions where Lazio could transition quickly.
“We are disappointed to have lost badly against a direct rival, but we mustn't make a tragedy out of it. We know that this isn't us, we were sluggish and ineffective, so we have to get back on track immediately for Wednesday.
“We wanted to give Diego Demme a rest, as he'd used up a lot of energy recently. We thought Fabian Ruiz could use his quality behind Gonzalo Escalante, but we were too slow and predictable."