NAC Breda coach Stijn Vreven admits Thierry Ambrose's season is over.
The on-loan Manchester City striker suffered a knee injury on Sunday against Willem II.
"This is tough for him. He's having a hard time with it," said Vreven.
"He had a good first year at the highest level, so it is painful for him to end up like that."
The coach added: "Manchester City now takes everything in its hands and determines what will happen. He will be doing his rehabilitation in Manchester, I will assume that."